Category Archives: General Use

Issues with Actively Scanning Virus Protection Applications and Data Acquisition and Processing

In many instances of instrument and processing stations being connected to the internet, I’ve helped individuals having system lock up issues on various mass spec systems over the past 20 years, when using Real-Time Virus Scanning Protection.

This issue is vendor agnostic and will causes problems in data collection and processing on a number of vendor platforms.

If you have Norton, McAfee, Microsoft Security Essentials/Windows Defender, etc and you need to run real-time virus protection. You should exclude the folders where data is actively being collected and processed. This will ensure that any processes, such as instrument communication, raw data writing to disk or processed result file creation,aren’t being interrupted by virus checking during data collection and manipulation.

Below is a list of folders recommended for exclusion in the various anti-virus programs.

The example comes from Windows Defender in Windows 10, and will have a different user interface dependent on what application you are using, however each application available commercially today has this capability.

1:Real-time protection is on and select settings

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2: Select Add an Exclusion

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3: Add each of these folders as an exclusion

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TraceFinder Webinar series in Begins in October


please click the link below for more information.

http://www.thermoscientific.com/content/tfs/en/about-us/events/tracefinder-webinar-series.html

Links to each webinar listed below:

 

Video – How to create NIST 2014 custom libraries with FreeStyle

To make custom libraries for use in TraceFinder 3.3 Unknown Analysis, the easiest way is to curate your spectra with FreeStyle and send to the NIST 2014 application which comes with the purchase of any NIST 2014 library.

TF 3.2 Setting up to Data Review to display Positive results first

In the video below, we have set up the flagging criteria to be able to sort and float Positive results, above the LOR/Cutoff Limit set in the method settings,to the top of the data review grid. We have also setup a flag to allow compounds with detected peaks but fall under the LOR/Cuttoff level in the QAQC section of the master/local method, to appear below the positive results. This should assist in labs wanting to review data by exception and to validate their data review process to incorporate into their SOPs to utilize this criteria.

TraceFinder 3.2 – New Quick Acquisition for Method Development

In previous versions of TraceFinder, there existed the Development Batch under the Method Development Mode of the application.

TraceFinder 3.2 has been replaced  with a new Quick Acquisition button in the toolbar and in the Tools menu items.

This allows the user to acquire a sequence of files and open them in either Qual Browser or FreeStyle, from any view or mode.

The main benefit is that the user can perform method development or simply acquire a file to test the system. This is done without having to utilize batch processing to get an quick answer to the question.

Video player has changed. If the picture appears blurry, in the top right hand corner of the player you can enable HD to play back high resolution video.

Thermo FreeStyle – Sequence Navigation tutorial

In the pending TraceFinder 3.2 release, FreeStyle will be an optional feature that comes with every installation.

FreeStyle is a new qualitative viewing package that is taking on the features of QualBrowser.

TraceFinder 3.2 gives you the ability to utilize both QualBrowser and Freestyle when analyzing data, from links within the application.

Please view the video below as a quick tutorial on the sequence navigation of FreeStyle.

Video player has changed. If the picture appears blurry, in the top right hand corner of the player you can enable HD to play back high resolution video.

Thermo Freestyle – General Navigation Tutorial

In the pending TraceFinder 3.2 release, FreeStyle will be an optional feature that comes with every installation.

FreeStyle is a new qualitative viewing package that is taking on the features of QualBrowser.

TraceFinder 3.2 gives you the ability to utilize both QualBrowser and Freestyle when analyzing data, from links within the application.

Please view the video below as a quick tutorial on the basic navigation of FreeStyle.

 

Video player has changed. If the picture appears blurry, in the top right hand corner of the player you can enable HD to play back high resolution video.

 

Note: FreeStyle is a separate application and will require a separate license from TraceFinder.

However, when you apply for a TraceFinder 3.2 license you will receive both a  TF license and a FreeStyle license.

You simply apply each to their respective license when using the applications together.

Peptide Quantitative Method Development with TF3.1

TF 3.0 – The Daily Technician Workflow – Point, Shoot and Read the report

Part of what makes TraceFinder a tool for the average chemist, is that complex experiments and processing can be setup once.

But then it can be used a thousand times, by technicians that just need to make samples and put them on the instruments to run.

Though there are many other things that can be done. Although, this isn’t an open access software, we have made it easy to just run your samples and get a report out on the fly that can go to a printer or to a pdf after each injection.

Please view the video below.

If the video is blurry please click the cog wheel at the bottom of the panel and increase the video display resolution.

How to do Background Subtraction w/ Qualbrowser

A couple of questions have come in, on how to best perform background or blank subtraction.

QualBrowser has a native tool to perform this task.

Please see the video below, on how to perform the operation on a single sample or a batch of samples using a .sld file.

If the video is blurry please click the cog wheel at the bottom of the panel and increase the video display resolution.