Disappearing Peaks – Master Method and Instrument Method not set correctly together

Last week at a customer site, the system was collecting information but no peaks were being detected and displayed.

If you opened the Raw files up in Qual browser and applied a layout AND selected autofilter the peaks for the compounds would appear correctly.

The issue was that the instrument method that had been updated in the master method did not collect information for the set quan mass. that is the filters in the rawfile looked something like this MS + SRM 906.01 [59.2-60.2] but the filter selection stored in the master method looked like this  MS + SRM 906.01 [59.3-60.3], and the extracted mass set in grid was set to 59.27.

Update scan filters

Video of update filter

About humphrjk

Product Manager for Analytical Software for Chemist. Analytical Chemist, Mass Spectrometry Scoutmaster Troop 4277 Skipper Ship 4277 Vice Commodore Texas Sea Scouts

Posted on March 5, 2012, in Method Development, Troubleshooting. Bookmark the permalink. Leave a comment.

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