Category Archives: Tutorial

Xcalibur Quan Method to TraceFinder Methods for Quan Conversion

Below is a quick and simple way to move from Xcalibur based quan methods to TraceFinder.

If the video is blurry please click the cog wheel at the bottom of the panel and increase the video display resolution.

 

Isotope Pattern Scoring in TF 3.1 – Answer to “Ask A Guru” Question

Below is an excerpt from the online help in TF 3.1.

A few questions have come up on how we calculate the isotope pattern score and visualization.

Here is the answer directly from the online documentation. Remember we do have comprehensive manuals and help under the Help Menu.

Link to PDF file: isotope scoring

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New In TraceFinder 3.1 – Sieve Unknown Screening Connector

TF 3.1 now includes a plugin kit, which allows for the rapid development of custom workflows within existing functionality of TF and external applications.

The first technology connection made is to Thermo Sieve 2.1.  This allows a user to send data to and receive selected results from Sieve. This gives TF the ability to complete the “Unknown to Known” workflow. This is accomplished by not reinventing unknown analysis inside of TF, but by leveraging the core competencies of TF and Sieve in a unified platform.

The video below is a short demo of how this works in an Unknown Analysis to Quantitative workflow, by Mark Sanders.

His accompanied ASMS poster is located on a previous posting.

The Power of Ease of Use – Is it TELEPATHY or TraceFinder 3.1? – Submitting a set of samples in realtime

Ya can get much easier in putting on a batch of samples to run, unless your telepathic.

Here is a set of sample just extracted and ready to run a method that was created for this bioanalytical assay.

The process is the same after the method development is done. It doesn’t matter if you are a GC, GCMS, LC or LCMS user.

It’s also no different whether you a clinical, environmental, food safety or just a general quan user. The power of TF is that it makes the technicians life, of data acquisition and review much easier.

If the video is blurry please click the cog wheel at the bottom of the panel and increase the video display resolution.

Method Development Unleashed – TF 3.1 and Multiple Instrument Methods

In an effort to help make TF a more friendly method development platform, we have introduced the ability to have an option to use multiple instrument methods in a batch of samples.

This ability is enabled simply by exposing the instrument method column in the sample definition grid.

When enabled the master method’s instrument selection is overridden, and the selected instrument method is used in its place.

This allows the user to have the same processing conditions but monitor the effects of chromatography differences on the peaks of interest.

Once an instrument method is optimized and chosen, simply turn off the column, update the Master Method and save.

All future batches of samples will use that instrument method.

See the video below.

If the video is blurry please click the cog wheel at the bottom of the panel and increase the video display resolution.

The Power of Comparing – Do these things go together? – TF 3.1: The NEW Comparative View in Data Review

Many have asked us, how to easily compare compound response across multiple samples.

Here is the answer.

Comparative View allows for a group of samples to be shown side by side with fixed Y-scale to the most intense or a selected threshold reference sample.

The view allows the user to visualize the Expected Retention Time and the Range of Time for peak detection via Markers. This will clearly indicate how the chromatography is responding.

The user can designate samples to be part of individual or multiple groups, by assigning alpha-numeric characters to column in the sample definition screen. Once assigned, and a member of the group is selected in the results grid, the multi-chromatogram pane will display the sample group in columns and the compounds in rows.

The use of a Threshold Sample and a new tab in the method under the Limits section, allows for a visual bar to be set for a specific peak height or a percentage of the Threshold Sample’s peak height.

Below is a video of the new feature in TraceFinder 3.1, debuting at ASMS 2013.

If the video is blurry please click the cog wheel at the bottom of the panel and increase the video display resolution.

The Power of Reporting – Is it Magic or Tracefinder3.1?…. New Preview of Report Designer with TF 3.1

One of the most requested features is to have an easier way to create custom reports.

Though TF has some great Standard Reports, and a really powerful VBA-Excel custom reporting tool. We’ve been investigating ways to make it easier to create custom reports.

The new Report Designer that will be in Preview form, debuts at ASMS 2013.

The learning curve is low, because it looks and feels like Microsoft Excel . Yet it is powerful, because you can do many the same special functions as Microsoft Excel.

Even if the Report Designer doesn’t have quite the feature you need, but Excel does, simply open the template in Excel from within the Designer. There you can make edits and save the template.

When you use the Excel edited template to create reports those edits are used.

As stated previously, this is a PREVIEW. This means that anyone can use the designer, but it is not a final commercial version.

If you wish to use it for reporting data, as with any custom report template, YOU must validate that the report template generates the correct information.

We will be looking for feedback on issues found or features to be added. Starting soon there will be a page on mytracefinder.com just for the Designer, where updates and feedback will be available.

Below is a video of how to use the Report Designer to create a simple report from a blank page.

The Report Designer uses the data from the currently opened Batch of Samples and results to model the data. This allows you to see exactly what the final report will look like when it’s produced within the application.

The video is a bit longer than usual but shows how simple it is to create a report which uses special features, such as formulas and conditional formating.

If the video is blurry please click the cog wheel at the bottom of the panel and increase the video display resolution.

Applying an external/historical curve to a batch of samples after Acquisition – Ask A Guru

The video below shows how to apply a calibration curve from one batch that contains calibration samples to a batch of samples that contain no calibrators.

This workflow is the same as selecting the external curve in the Acquisition workflow, but may be used on any batch of samples after acquisition.

The features allows the user to run a calibration batch in the morning and use that curve for all subsequent batches for the time period their SOP allows.

HMMMMMM… Maybe your day just got alittle easier.

If the video is blurry please click the cog wheel at the bottom of the panel and increase the video display resolution.

TF 3.0 Walkthrough Slide Show

The video below is a slideshow of a Power Point presentation of key elements of TF 3.0.

 

Storing and Using Data on a Mapped Network Drive

Recently, an “Ask A Guru”, question came through asking how to have data on any other drive besides C:.

 

In the video below, the process of how to set the root directory structure that TraceFinder needs to find data on any drive is shown.

Once created you can move whole projects with the Windows Explorer tool, or you can  use either the “Save As” to make a copy or the “Move” File-Menu item top move the batch to the new disk.

If you have a network shared directory, that you want to use, simply map that drive to your windows directory. It will then function as any other attached drive with the exception of being able to acquire data across the network.

If the video is blurry please click the cog wheel at the bottom of the panel and increase the video display resolution.