Category Archives: Videos

The Power of Comparing – Do these things go together? – TF 3.1: The NEW Comparative View in Data Review

Many have asked us, how to easily compare compound response across multiple samples.

Here is the answer.

Comparative View allows for a group of samples to be shown side by side with fixed Y-scale to the most intense or a selected threshold reference sample.

The view allows the user to visualize the Expected Retention Time and the Range of Time for peak detection via Markers. This will clearly indicate how the chromatography is responding.

The user can designate samples to be part of individual or multiple groups, by assigning alpha-numeric characters to column in the sample definition screen. Once assigned, and a member of the group is selected in the results grid, the multi-chromatogram pane will display the sample group in columns and the compounds in rows.

The use of a Threshold Sample and a new tab in the method under the Limits section, allows for a visual bar to be set for a specific peak height or a percentage of the Threshold Sample’s peak height.

Below is a video of the new feature in TraceFinder 3.1, debuting at ASMS 2013.

If the video is blurry please click the cog wheel at the bottom of the panel and increase the video display resolution.

The Power of Reporting – Is it Magic or Tracefinder3.1?…. New Preview of Report Designer with TF 3.1

One of the most requested features is to have an easier way to create custom reports.

Though TF has some great Standard Reports, and a really powerful VBA-Excel custom reporting tool. We’ve been investigating ways to make it easier to create custom reports.

The new Report Designer that will be in Preview form, debuts at ASMS 2013.

The learning curve is low, because it looks and feels like Microsoft Excel . Yet it is powerful, because you can do many the same special functions as Microsoft Excel.

Even if the Report Designer doesn’t have quite the feature you need, but Excel does, simply open the template in Excel from within the Designer. There you can make edits and save the template.

When you use the Excel edited template to create reports those edits are used.

As stated previously, this is a PREVIEW. This means that anyone can use the designer, but it is not a final commercial version.

If you wish to use it for reporting data, as with any custom report template, YOU must validate that the report template generates the correct information.

We will be looking for feedback on issues found or features to be added. Starting soon there will be a page on mytracefinder.com just for the Designer, where updates and feedback will be available.

Below is a video of how to use the Report Designer to create a simple report from a blank page.

The Report Designer uses the data from the currently opened Batch of Samples and results to model the data. This allows you to see exactly what the final report will look like when it’s produced within the application.

The video is a bit longer than usual but shows how simple it is to create a report which uses special features, such as formulas and conditional formating.

If the video is blurry please click the cog wheel at the bottom of the panel and increase the video display resolution.

Interesting Video of Carbon Atoms from IBM

Below is a video and short story from the BBC about the use of a tunneling electron microscope to visualize individual atoms of carbon on a copper substrate. A key note that I took away from this is that with this technology they are able to ovserve the bonds of molecules, which over time could have profound effects on Mass Spectrometry and our understaning of fragmentation pathways. This would help in constructing databases of molecular properties and predictive MSn methods.

As much fun as TF 3.0 has been to introduce to you all. I’m taking alittle breather and getting material ready for the next BIG release at ASMS.

Soon as we get clearance to share some info to the world There will be new videos daily.

Plus an ebook called “The Guru’s Guide to TraceFinder”, available as a page on th blog, or as an iBook for iPhone/iPad and an EPUB format for Kindle and Android. This will be a pocket guide for those times you don’t have access to the blog.

Applying an external/historical curve to a batch of samples after Acquisition – Ask A Guru

The video below shows how to apply a calibration curve from one batch that contains calibration samples to a batch of samples that contain no calibrators.

This workflow is the same as selecting the external curve in the Acquisition workflow, but may be used on any batch of samples after acquisition.

The features allows the user to run a calibration batch in the morning and use that curve for all subsequent batches for the time period their SOP allows.

HMMMMMM… Maybe your day just got alittle easier.

If the video is blurry please click the cog wheel at the bottom of the panel and increase the video display resolution.

TF 3.0 Walkthrough Slide Show

The video below is a slideshow of a Power Point presentation of key elements of TF 3.0.

 

My Filter String Is Missing After I Updated My Methods Associated Rawfile.. HMMMMMM

So in both the local and master methods, a user can update the associated rawfile to see the peaks they are looking for.

This dialog has an option to update the filter strings. Which makes it easy to do especially if you have hundereds of compounds.

Associate rawfile

When you do this, the logic looks to the compound database info that is in the Acquisition list and to help it determine the filter with the right precusor and then the extracted ion setting to see which filter contains its value within the range of product ions in the brakets of the mass filter. If everything matches from the newly selected rawfile it sets the filter accordingly. If it doesn’t then the compound will have a little red dot next to its name and a missing filter error lights up.

This typically occurs when the new file has a slightly different filter string and the method’s extracted mass falls outside of the product mass range of the filter.

The following video shows you how to manually fix this issue.

If the video is blurry please click the cog wheel at the bottom of the panel and increase the video display resolution.

Storing and Using Data on a Mapped Network Drive

Recently, an “Ask A Guru”, question came through asking how to have data on any other drive besides C:.

 

In the video below, the process of how to set the root directory structure that TraceFinder needs to find data on any drive is shown.

Once created you can move whole projects with the Windows Explorer tool, or you can  use either the “Save As” to make a copy or the “Move” File-Menu item top move the batch to the new disk.

If you have a network shared directory, that you want to use, simply map that drive to your windows directory. It will then function as any other attached drive with the exception of being able to acquire data across the network.

If the video is blurry please click the cog wheel at the bottom of the panel and increase the video display resolution.

 

TF 3.0 – The Daily Technician Workflow – Point, Shoot and Read the report

Part of what makes TraceFinder a tool for the average chemist, is that complex experiments and processing can be setup once.

But then it can be used a thousand times, by technicians that just need to make samples and put them on the instruments to run.

Though there are many other things that can be done. Although, this isn’t an open access software, we have made it easy to just run your samples and get a report out on the fly that can go to a printer or to a pdf after each injection.

Please view the video below.

If the video is blurry please click the cog wheel at the bottom of the panel and increase the video display resolution.

TF 3.0 – How to add Adducts for use in the Compound Database

The video below shows how to edit the positive and negative adducts that can be used in the CDB.

The use of adducts becomes very useful in calcualtions of the exact masses for screening and high resolution quantitation.

This also helps in the screening qualitiy measurement of isotope confirmation and identification.

If the video is blurry please click the cog wheel at the bottom of the panel and increase the video display resolution.

How to do Background Subtraction w/ Qualbrowser

A couple of questions have come in, on how to best perform background or blank subtraction.

QualBrowser has a native tool to perform this task.

Please see the video below, on how to perform the operation on a single sample or a batch of samples using a .sld file.

If the video is blurry please click the cog wheel at the bottom of the panel and increase the video display resolution.